Born in Burbank, California, to entertainers Connie Stevens and Eddie Fisher, Fisher was named Miss Golden Globe at the 1992 Golden Globe awards and would go on to be a triple threat in television, musical theater and motion pictures. After her Broadway debut as Rizzo in Grease, she made a  “sensational and sexy” turn as Sally Bowles in Sam Mendes and Rob Marshall’s critically acclaimed Broadway revival of Cabaret, which earned her rave reviews.

However, it was her five seasons as the monstrously ambitious and seductive Hollywood executive Paige Clark on the groundbreaking ABC show Ellen that introduced her to television audiences around the world and earned her a Golden Globe nomination. She next starred opposite John Goodman in FOX's series Normal, Ohio, playing the hilariously fascinating combo of a young caring mother who just happened to be a "bit of a slut." She also spent two seasons starring in her own series, Wild Card, for Lifetime. In 2005, Fisher joined the cast of the hit television series Desperate Housewives as Felicity Huffman’s boss, Nina Fletcher. She then returned to television opposite Brad Garrett for four seasons in FOX’s ‘Till Death. She also appeared in a recurring role on ABC’s Last Man Standing. Her crowning achievement to date was starring with Matthew Broderick in the hit Disney film Inspector Gadget.